Secretin MRCP


A Secretin Magnetic Resonance Cholangiopancreatography (S-MRCP) is a specialized, dynamic MR Pancreatography exam performed following the administration of Secretin, a medication that simulates the hormone that causes liver and pancreas secretion. This procedure uses a magnetic field, radio waves, and a computer to create detailed cross-sectional images of the liver, gallbladder, bile ducts, pancreas, and pancreatic duct. Our team of sub-specialized physicians utilizes S-MRCP to:

  • Detect tumors, stones, inflammation or infection
  • Evaluate patients with pancreatitis to determine the underlying cause, assess for long-term scarring, and determine the amount of healthy pancreatic function and secretions
  • Provide your referring physician with valuable information for surgical and treatment planning

This exam does not use radiation but does involve:

  • The placement of an IV that will be used to inject Secretin. (If health professionals commonly encounter difficulty finding your veins when drawing blood, please let us know so that extra time can be added to your appointment.)


To make registration quicker and easier, we encourage you to take advantage of our online system, where you will complete the MRI Screening Questionnaire and the MRI and Pregnancy form (if applicable).

If you are claustrophobic (fearful of small, enclosed areas) or experience pain when lying on your back for more than 30 minutes, your referring physician may prescribe a relaxant or pain medication to help you through the exam. When scheduling your appointment, please make the IMI Team aware of any concerns or issues you might have, so we can ensure that you have everything you need to comfortably, successfully complete your MRI exam.

While we don’t anticipate a long wait, we do want to make any waiting time as pleasant as possible. Please consider bringing a magazine, book or music with headphones to help you pass the time.

Please do not eat or drink anything for four hours before your arrival.

Unless you are told otherwise, you may take your medications as usual.

Please leave all jewelry and valuables at home.


Please inform the technologist, radiology nurse, and or radiologist of any allergies you may have, or if you are pregnant or nursing.

If you have not already done so online, you will be asked to fill out a questionnaire to determine if an MRI is safe for you. Because an MRI utilizes a strong magnetic field, patients with various implants (usually metallic), body piercings, or other metal in their bodies (including some tattoos) may encounter difficulty with an MRI. It is critical that your imaging physician is made aware of any such potential issues before your examination. For more important safety information regarding metals and MRI, please visit our MRI, What to Expect page to learn more.

You will be asked to wear scrubs during the exam. Our nurses will discuss any questions you may have prior to your exam.


You may be asked to drink approximately 16 ounces of organic blueberry juice 10 to 20 minutes prior to your MRI imaging. The blueberry juice serves as a contrast agent to improve imaging of the stomach and duodenum.

For this type of exam, an IV is required to inject a medication called Secretin; this injection can last for up to one minute.

An MRI machine consists of a large, cylinder-shaped tube with a moveable scanning table that slides into the center of the machine. For this exam, you will be asked to lie head-first on the table with your arms at your sides.

Coils (special devices to improve image quality) will be placed on or around your abdomen.

The scanning table will slide your entire body into the magnet. During the scan, you may feel a slight vibration and will hear intermittent humming, thumping, clicking and knocking sounds. Headphones will be provided to help mask the noise and allow you to listen to music. As your images are taken, you must hold very still and at times may be asked to hold your breath.

The technologist will able to see and hear you at all times during the exam.

The MRI exam will take approximately 2.5 to 3 hours, depending on the specifics that your referring physician has ordered.


Once your exam is complete, there will be no restrictions placed upon you. You may eat, drive, and resume your activities as usual. Your images will be examined by a radiologist and their report sent to your healthcare provider within 24-48 hours of your examination. Your healthcare provider will review the results with you.

Request a Price Quote